MIGRAINE SYMPTOMS IN PATIENTS WITH MRI WHITE MATTER HYPERINTENSITY AFTER AND BEFORE TREATMENT

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Mehrnoosh Ebadi, Mohsen Ebrahimimonfared, Reza Sadeghi, Alireza Rezaei Ashtiani, Amir Mohammad Eghbalnejad Mofrad, Fardin Faraji, Maryam Mohammadi

Abstract

Objective and background: Migraine is one of the most common diseases and causes of parenchymal lesions in the brain, which is associated with symptoms of nausea and vomiting, visual impairment, and olfaction. One way to diagnose migraine headaches is to study magnetic resonance imaging (MRI). MRI T2 hyperintense lesions in migraines are usually found in the white matter and sometimes in the cerebral cortex.
Methods: 114 patients with informed consent were included in the study. They were then referred for MRI. Patients were then divided into two case and control groups according to the presence or absence of lesion in MRI. A complete neurological examination was performed, and clinical symptoms were recorded. The MIDAS headache questionnaire was. After three months of the treatment period, the patients again filled up the MIDAS questionnaire, and a complete neurological examination was performed.
Results: In this study, 101 patients with migraines were studied. Also, in a separate survey of patients’ symptoms with headaches, the frequency of visual aura and night headache was statistically significant in both groups. The results show no significant difference between the mean scores of Midas after treatment in the two groups. The results show that the mean scores of Midas after the study decreased in all patients with abnormal MRI. But in patients who have lesions in BS, the mean scores of Midas have not been significant.
Conclusion: the mean score of Midas before starting treatment in the group whose brain MRI was normal was 33.06, and in the group whose brain MRI was abnormal was 55.15, which in statistical studies was significant. In this study, it was observed that the Midas score decreased significantly after starting treatment.

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