Study Of The Toxicological Effects Of Pentostam And Silver Nanoparticles On Liver And Spleen Tissue In Albino Mice Infected With Cutaneous Leishmaniasis

Abstract

Cutaneous Leishmaniasis (CL) is a parasitic disease that has been known to humans for centuries, and which are called by many local names and were causing suffering and death to people infected with it, The results also showed that pentostam (Sb), silver nanoparticles (AgNPs) and loaded drug (AgNPs + Sb) had different toxic effects on liver and spleen tissue, as it was higher on liver and spleen tissues when using pentostam compared with free silver nanoparticles and loaded silver nanoparticles .The drug Pentostam, which did not show clear pathological effects on the tissues of the liver and spleen.